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Consider the following factors when selecting an initial dose of Methadose:
- Total daily dose, potency, and prior opioid the patient has been taking before;
- Patient’s degree of opioid experience and opioid tolerance;
- General condition and medical status of the patient;
- Concurrent medication;
Type and severity of the patient’s pain (Methadose (Methadone HCL) 40mg)
Also, consider the following important factors that differentiate methadone from other opioid analgesics:
- The peak respiratory depressant effect of methadone occurs later. So, it persists longer than its peak analgesic effect.
- There is high interpatient variability in absorption, metabolism, and relative analgesic potency. Methadose (Methadone HCL) 40mg
- The duration of analgesic action of methadone is 4 to 8 hours (based on single-dose studies). So, Buy Methadose 40mg Dispersible Tablet.
- Methadone has a narrow therapeutic index, especially when combined with other drugs. So, Where To Buy Methadone Liquid Online
The following serious adverse reactions.
- Respiratory Depression
- QT Prolongation
- Chronic Pulmonary Disease
- Head Injuries and Increased Intracranial Pressure
- Interactions with Other CNS Depressants
- Hypotensive Effect
- Gastrointestinal Effects
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