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That’s a question I’m accustomed to hearing from leery patients and families. When I inform them that their physician has ordered Methadone for pain. While it’s true that methadone treats narcotic withdrawal symptoms. Methadone is also a very effective medication to treat moderate to severe pain. online pharmacy without scripts.
Morphine has earned the title of the Gold Standard for pain control. So, other opioids compared with it because of its effectiveness. Ease of administration and low cost. If morphine is so great, why would we ever use methadone?
If we’re going to start comparing methadone with morphine, we need to start with pain. They are two types pain. Physiological explanations: nociceptive and neuropathic. Nociceptive pain is generally caused by tissue injury. Neuropathic pain is injury to nerves in the central nervous system. online pharmacy without scripts.
We have opiate receptors in our brains that allow us to respond to opioid pain medications. The majority of these receptors are mu and delta receptors and a smaller percentage are NMDA. Mu receptors mediates Nociceptive pain. And neuropathic pain by delta and NMDA receptors. Morphine binds to mu receptors only, while methadone binds to mu, delta, and NMDA. Morphine does an excellent job of treating many types of pain. But because of its ability to bind to 100% of opiate receptors, methadone may do it even better.